Tharick A Pascoal Selected Research

AZD4694

2/2022	Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease.
2/2022	Comparing tau status determined via plasma pTau181, pTau231 and [18F]MK6240 tau-PET.
1/2022	Association of locus coeruleus integrity with Braak stage and neuropsychiatric symptom severity in Alzheimer's disease.
10/2021	APOEε4 potentiates the relationship between amyloid-β and tau pathologies.
1/2021	Interactive rather than independent effect of APOE and sex potentiates tau deposition in women.
1/2021	Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment.
1/2021	Association between regional tau pathology and neuropsychiatric symptoms in aging and dementia due to Alzheimer's disease.
1/2020	Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.

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Tharick A Pascoal Research Topics

Disease

40	Alzheimer Disease (Alzheimer's Disease) 02/2022 - 01/2017
26	Cognitive Dysfunction 02/2022 - 01/2016
20	Dementia (Dementias) 02/2022 - 06/2017
6	Atrophy 02/2022 - 01/2016
4	Disease Progression 01/2022 - 04/2016
3	Frontotemporal Dementia (Semantic Dementia) 01/2022 - 01/2020
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 01/2020
3	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2020 - 03/2017
2	Tauopathies 01/2022 - 01/2019
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 12/2021
1	Gliosis 12/2021
1	Glucose Intolerance 01/2021
1	Corticobasal Degeneration 01/2020
1	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2020
1	Brain Diseases (Brain Disorder) 12/2019
1	Neuroinflammatory Diseases 01/2018
1	Body Weight (Weight, Body) 03/2017

Drug/Important Bio-Agent (IBA)

32	Amyloid (Amyloid Fibrils)IBA 02/2022 - 03/2017
24	Biomarkers (Surrogate Marker)IBA 02/2022 - 01/2017
8	AZD4694IBA 02/2022 - 01/2020
6	florbetapirIBA 10/2021 - 06/2017
4	Amyloid beta-PeptidesIBA 02/2022 - 10/2021
4	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 10/2021 - 01/2020
3	Apolipoproteins E (ApoE)IBA 01/2021 - 12/2020
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2017
2	Biological ProductsIBA 01/2022 - 01/2022
2	Glucose (Dextrose)FDA LinkGeneric 12/2021 - 07/2019
2	ApolipoproteinsIBA 01/2021 - 01/2020
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2021 - 01/2018
2	THK5351IBA 01/2019 - 03/2017
1	EpitopesIBA 02/2022
1	Indicators and Reagents (Reagents)IBA 02/2022
1	neuromelaninIBA 01/2022
1	Amino Acids FDA Link 12/2021
1	CarbonIBA 12/2021
1	Cell Adhesion MoleculesIBA 12/2021
1	Protein Isoforms (Isoforms)IBA 12/2021
1	Glial Fibrillary Acidic ProteinIBA 12/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	RadiopharmaceuticalsIBA 01/2021
1	Threonine (L-Threonine)FDA Link 01/2020
1	FluorineIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2019
1	rasagiline (Azilect)FDA Link 01/2019
1	Monoamine Oxidase (MAO)IBA 01/2019
1	Cytochrome P-450 CYP2C19IBA 02/2018
1	Chitinase-3-Like Protein 1IBA 01/2018
1	visininIBA 01/2018
1	Synaptosomal-Associated Protein 25IBA 01/2018
1	tau Proteins (tau Protein)IBA 06/2017
1	Protein AggregatesIBA 01/2016

Therapy/Procedure

2	Therapeutics 11/2017 - 04/2016
1	Precision Medicine 01/2018